Publications

Dall'Agnese G, Hannett NM, Overholt KJ, Platt JM, Henninger JE, Marcos-Vidal A, Othman Z, Salgado G, Antoniali G, Tell G.  2025.  APE1 condensation in nucleoli of non-cancer cells depends on rRNA transcription and forming G-quadruplex RNA structures.. Nucleic Acids Res. 53(5)

Dall'Agnese A, Zheng MM, Moreno S, Platt JM, Hoang AT, Kannan D, Dall'Agnese G, Overholt KJ, Sagi I, Hannett NM et al..  2025.  Proteolethargy is a pathogenic mechanism in chronic disease.. Cell. 188(1):207-221.e30.

Dejosez M, Dall'Agnese A, Ramamoorthy M, Platt J, Yin X, Hogan M, Brosh R, Weintraub AS, Hnisz D, Abraham BJ et al..  2023.  Regulatory architecture of housekeeping genes is driven by promoter assemblies.. Cell Rep. 42(5):112505.

Dall'Agnese A, Platt JM, Zheng MM, Friesen M, Dall'Agnese G, Blaise AM, Spinelli JB, Henninger JE, Tevonian EN, Hannett NM et al..  2022.  The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance.. Nat Commun. 13(1):7522.

Banani SF, Afeyan LK, Hawken SW, Henninger JE, Dall'Agnese A, Clark VE, Platt JM, Oksuz O, Hannett NM, Sagi I et al..  2022.  Genetic variation associated with condensate dysregulation in disease.. Dev Cell. 57(14):1776-1788.e8.

Johnnidis JB, Muroyama Y, Ngiow SFoong, Chen Z, Manne S, Cai Z, Song S, Platt JM, Schenkel JM, Abdel-Hakeem M et al..  2021.  Inhibitory signaling sustains a distinct early memory CD8+ T cell precursor that is resistant to DNA damage.. Sci Immunol. 6(55)

Seiglie J, Platt J, Cromer SJane, Bunda B, Foulkes AS, Bassett IV, Hsu J, Meigs JB, Leong A, Putman MS et al..  2020.  Diabetes as a Risk Factor for Poor Early Outcomes in Patients Hospitalized With COVID-19.. Diabetes Care. 43(12):2938-2944.

Li CH, Coffey EL, Dall'Agnese A, Hannett NM, Tang X, Henninger JE, Platt JM, Oksuz O, Zamudio AV, Afeyan LK et al..  2020.  MeCP2 links heterochromatin condensates and neurodevelopmental disease.. Nature. 586(7829):440-444.

Klein IA, Boija A, Afeyan LK, Hawken SWilson, Fan M, Dall'Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR et al..  2020.  Partitioning of cancer therapeutics in nuclear condensates.. Science. 368(6497):1386-1392.

Li DK, Platt JM, Shay JES, Yarze JC.  2019.  Sterile cerebrospinal fluid ascites presenting as high SAAG ascites: a case report.. BMC Gastroenterol. 19(1):200.

Henderson A, Wu Y, Huang YChuan, Chavez EA, Platt J, F Johnson B, Brosh RM, Sen D, Lansdorp PM.  2017.  Detection of G-quadruplex DNA in mammalian cells.. Nucleic Acids Res. 45(10):6252.

Frigault MJ, Lee J, Basil MCiocca, Carpenito C, Motohashi S, Scholler J, Kawalekar OU, Guedan S, McGettigan SE, Posey AD et al..  2015.  Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells.. Cancer Immunol Res. 3(4):356-67.

Platt JM, Ryvkin P, Wanat JJ, Donahue G, M Ricketts D, Barrett SP, Waters HJ, Song S, Chavez A, Abdallah KOmar et al..  2013.  Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence.. Genes Dev. 27(12):1406-20.

Arai R, Kobayashi N, Kimura A, Sato T, Matsuo K, Wang AF, Platt JM, Bradley LH, Hecht MH.  2012.  Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20.. J Phys Chem B. 116(23):6789-97.

Wise DR, Ward PS, Shay JES, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, DeMatteo RG, M Simon C, Thompson CB.  2011.  Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.. Proc Natl Acad Sci U S A. 108(49):19611-6.